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Pharmaceutical Packaging Companies

Last updated: January 2026

This directory lists 90 pharmaceutical packaging companies across the United States, from primary sterile filling specialists to secondary blistering and bottling operations.

Buyers engage these specialized partners to solve critical problems such as achieving rapid market entry for new drug products, expanding existing product lines efficiently, or enhancing compliance with complex regulatory frameworks like DSCSA for serialization. They provide the necessary infrastructure and expertise to handle intricate packaging formats, manage cold chain logistics, and ensure the stringent quality controls mandated by cGMP.

The landscape of pharmaceutical packaging suppliers includes dedicated contract packagers (CPs) who focus solely on packaging services, and larger Contract Manufacturing Organizations (CMOs) that offer integrated manufacturing and packaging. There are also highly specialized firms focusing on niche areas like aseptic filling, ophthalmic products, or those with extensive experience in Child-Resistant (CR) and Senior-Friendly (SF) packaging designs for specific markets.

Successful engagement requires buyers to arrive with well-defined product specifications, clear volume forecasts, and a comprehensive understanding of their regulatory requirements, including stability testing data. Suppliers, in turn, expect detailed User Requirement Specifications (URS), a willingness to participate in rigorous auditing processes, and transparent communication regarding product characteristics and market distribution.

A significant trend in this category is the escalating demand for flexible, smaller-batch packaging capabilities driven by personalized medicine and orphan drugs, alongside a continued push for advanced serialization integration across all levels of packaging. Furthermore, increasing scrutiny on environmental impact is fostering innovation in sustainable packaging materials and processes, without compromising product integrity or regulatory compliance.

90 companies·63 emails·77 phones

Company Directory

90 companies nationwide

Cookeville, TN

Aphena Pharma Solutions is a U.S.-based contract pharmaceutical manufacturing and packaging company with two FDA-registered facilities. The company offers a wide array of turnkey services, handling solid dose, liquids, gels, creams, ointments, and biologics. It serves the prescription pharmaceutical, OTC, dietary supplement, and medical device marketplaces.

Carlsbad, CA

Based in Carlsbad, CA, Bay Area Bottles provides premium quality plastic containers for various commercial applications. They specialize in packaging solutions designed for industries such as personal care, nutraceuticals, pharmaceuticals, and food sectors, offering a diverse range of container options for their clients.

BD manufactures and sells prefillable drug delivery systems for pharmaceutical and biotech companies. They integrate these with connected care platforms and diagnostic solutions, focusing on advancing global health through their medical technologies and life sciences offerings.

Fort Worth, TX

Chubby Gorilla is a Southern California-based specialty packaging company, globally recognized for its child-resistant innovations. They manufacture a diverse range of containers, including bottles, dispensing containers, and tubes, designed for applications requiring child-resistant features in various industries.

Placentia, CA

Cleanroom Film and Bags manufactures custom cleanroom and sterile packaging solutions. With over 35 years of experience, they serve medical, pharmaceutical, electronic, aerospace, and food industries. Their ISO 9001:2015 certified, vertically integrated facilities produce high-quality products using pure resins, guaranteeing no reground or repurposed materials.

Cold Chain Technologies provides comprehensive thermal packaging solutions for the life sciences industry globally. Specializing in insulated packaging, the company ensures product safety and integrity throughout the cold chain. They serve various segments including manufacturers, distributors, clinical trials, and specialty pharmacies with qualified packaging.

Elk River, MN

Based in Elk River, MN, Cretex Medical offers contract manufacturing and engineering services for medical devices. They provide sterile packaging, complete kitting, and labeling, backed by ISO 13485 certification and FDA registration. Cretex ensures robust quality systems, helping clients efficiently launch and scale products.

Edison, NJ

Cryopak specializes in comprehensive cold chain packaging solutions, providing temperature-controlled packaging for sensitive products. They offer solutions designed to maintain specific temperature ranges during transport and storage, crucial for industries like pharmaceuticals. Based in Edison, NJ, Cryopak directly supplies essential packaging components to ensure product integrity.

Lowville, NY

Based in Lowville, NY, Custom Box Line provides custom packaging solutions, specifically serving the pharmaceutical industry. The company utilizes state-of-the-art packaging machines to print and process tailored boxes, offering fast turnaround times. They feature premium quality luxury packaging and a range of strong, sustainable card stock materials.

Queens Village, NY

Custom Divine Boxes specializes in providing high-quality custom packaging solutions, including secure and fashionable pharma boxes. They offer a wide range of options, from custom inserts to stunning printing, tailored to client visions and budgets. Based in Queens Village, NY, with an additional office in Fremont, CA, the company serves businesses seeking tailored packaging.

Council Bluffs, IA

Decker Packaging And Plastics, based in Council Bluffs, IA, offers custom flexible packaging solutions. They manufacture bags, liners, tubing, roll stock, and film, providing custom printing. Serving diverse markets, including medical, retail, and agricultural, the company focuses on durable packaging designed for product protection and sterility.

Woodstock, IL

Based in Woodstock, IL, Dordan is a family-owned thermoform packaging manufacturer specializing in custom medical trays, dunnage trays, clamshells, and blisters. The company provides thermoformed packaging solutions with capabilities like cleanroom manufacturing, serving the medical and pharmaceutical industries since 1962.

Boyertown, PA

Based in Boyertown, PA, Drug Plastics & Glass Co., Inc. manufactures high-quality plastic bottles and compatible closures. They serve the pharmaceutical industry, providing packaging for medicines, supplements, and lifestyle products. The company offers the industry's largest selection of bottle molds and custom solutions, including various child-resistant closure styles.

Paso Robles, CA

Based in Paso Robles, CA, Eagle Medical Inc. provides contract packaging, sterilization, and quality assembly for medical products. Certified to ISO 13485:2016, the company offers robust solutions for medical device packaging, aiming to optimize sterilization methodologies and accelerate market entry for its clients.

Costa Mesa, CA

Endural, based in Costa Mesa, CA, specializes in manufacturing high-grade plastic storage, transportation, and custom material handling containers. They offer an extensive selection of plastic poly cases and bespoke hard plastic solutions. The company produces various containers, pans, and trays specifically for pharmaceutical applications, emphasizing durable and reusable options.

ePac Flexible Packaging provides custom flexible packaging solutions, including standup and lay flat pouches, and rollstock. They offer child-resistant pouches, independently tested and certified to meet federal requirements. Specializing in health, beauty, and supplement industries, the company supports brands of all sizes with fast turnaround.

Vernon, CA

Based in Vernon, CA, Green Earth Packaging supplies wholesale eco-friendly packaging. They offer a diverse range of products including jars, bottles, bags, and containers, serving various industries. Specializing in pharmaceutical packaging, they provide essential child-resistant and tamper-evident solutions to ensure product security and compliance.

Swanton, OH

Based in Swanton, OH, Guardian Medical designs and manufactures novel terminally sterile packaging for medical implants. They offer integrated seal and rigid packaging systems, including custom solutions for complex devices. Their CapSure™ packaging provides superior protection, a reduced footprint, and supports sustainability goals with recyclable materials.

Sebastian, FL

Impak Corporation specializes in child-resistant pouches, available in multiple sizes and zipper formats. They offer custom printing and labeling options for their packaging solutions, designed to prevent accidental ingestion of poisons by children. The company serves industries requiring secure and compliant packaging.

Imperial Printing & Paper Box Manufacturing Co. is a custom folding carton manufacturer specializing in custom packaging and printed boxes. They provide custom pharmaceutical packaging boxes, emphasizing design and product protection. The company is ISO 9001 certified, environmentally conscious, and utilizes 100% renewable energy.

Salt Lake City, UT

Based in Salt Lake City, Industrial Container offers a diverse range of packaging solutions, including plastic jugs, drums, glass vials, and jars. These containers are designed to meet various industrial needs, providing suitable options for businesses requiring robust and specific packaging for their products.

IPC Pack is a US-based manufacturer specializing in advanced cold chain and temperature-controlled packaging. They design and produce insulated box liners, delivery bags, and pouches from paper, foam, and reflective materials. Their custom products protect frozen and refrigerated shipments for various industries, supporting durations up to 48 hours.

Brocton, NY

Based in Brocton, NY, Jamestown Plastics specializes in custom plastic thermoforming, providing diverse packaging solutions for medical and consumer industries. They offer certified child-resistant packaging, blister packaging, and medical device packaging. With over 67 years of experience, the company designs tailored solutions to improve efficiency and reduce costs.

Keystone Box Company specializes in child-resistant packaging solutions for the pharmaceutical industry. Their offerings are designed to prevent accidental ingestion, meet stringent safety regulations, and support sustainability goals. They provide essential packaging that ensures product integrity and consumer safety for pharmaceutical clients.

Earth City, MO

Legacy Pharma Solutions, based in St. Louis, MO, is a contract pharmaceutical packaging company. They specialize in high-speed bottle filling, blistering, unit-of-use, and secondary packaging solutions. Operating cGMP compliant facilities, they serve branded, generic, government, wholesale, and major retail pharmaceutical markets with robust quality controls.

San Diego, CA

Based in San Diego, CA, L + L Printers specializes in providing comprehensive design services for pharmaceutical and medicine packaging. The company assists healthcare and medical clients in developing custom packaging solutions tailored to their specific product needs and regulatory requirements.

Flemington, NJ

Medical Packaging Inc., LLC (MPI) provides comprehensive unit dose medication packaging and labeling systems, manufacturing a full range of equipment and materials. They support pharmaceutical and medical market clients with regulatory and technical expertise via their Drug Master File. MPI serves specialty pharma, hospitals, and extended care facilities.

Burlingame, CA

Merrill's Packaging specializes in critical packaging solutions for the medical device, pharmaceutical, and life sciences industries. With over 60 years of experience, the company offers custom thermoforming, design, and engineering services, creating new designs or reverse engineering existing packaging.

Greenville, SC

Multi-Pack Solutions is a Greenville, SC-based contract manufacturer offering turnkey contract manufacturing and packaging services. The company specializes in comprehensive solutions for product assembly and packaging requirements, serving various industrial clients. They focus on efficient, high-quality production to meet diverse packaged goods needs.

Gurnee, IL

Based in Gurnee, IL, Nosco is a full-service packaging solutions provider focused on the healthcare industry. They offer cartons, labels, inserts, and flexible packaging, specializing in child-resistant and compliant solutions for pharmaceutical, biotech, and medical device clients. Services include design, printing, and finishing.

Hanover, NJ

Based in Hanover, NJ, Nutra-Med Packaging LLC offers contract packaging services for pharmaceutical companies. Their FDA registered, cGMP compliant, and UL audited facilities provide turn-key solutions. Established in 1999, the company maintains a strong focus on quality control and efficient turn-around solutions for clients.

Syosset, NY

Based in Syosset, NY, Onyx Packaging is a full-service contract pharmaceutical packaging and manufacturing organization (CDMO). They provide primary and secondary packaging solutions like blister and bottle filling for sterile injectables, oral solids, and medical devices. Their cGMP compliant US facilities ensure reliable pharmaceutical supply chain support.

Richardson, TX

Based in Richardson, TX, OXO Packaging offers custom printed packaging solutions for various industries. They specialize in a range of boxes, including medicine boxes and CBD gift boxes, designed to meet US government regulatory standards. The company provides high-quality custom boxes with a flexible process, no die & plate charges, and quick turnaround times.

Sugar Land, TX

Based in Sugar Land, TX, Packhit provides custom-printed pharmaceutical packaging boxes and design services. They offer tailor-made designs, various styles, and materials to help brands contain, protect, and present products. Packhit emphasizes durable, recyclable, and eco-friendly packaging solutions for brand owners.

PCI Pharma Services is a CDMO providing integrated end-to-end drug development, manufacturing, and packaging solutions. The company offers advanced drug delivery and drug device combination product capabilities, including final assembly, pack, and test services, specializing in sterile fill-finish and lyophilization for injectable products.

Elyria, OH

Pharmacy-Lite Packaging, a U.S. manufacturer since 1991, provides streamlined, eco-friendly prescription vial systems and caps. They offer biodegradable, automation-compatible packaging solutions, including their Simple & Safe 2 Cap and EZ One Vial systems for liquid and dry scripts, serving independent pharmacies.

Clinton, TN

Based in Clinton, TN, Pharma Packaging Solutions provides specialized pharmaceutical packaging services. The company focuses on high-quality vial and ampule labeling for biopharma products. As a division of Carton Service Inc., they offer agile, compliant, and innovative solutions for the healthcare industry.

Isaacs, MD

Pillumina specializes in sustainable pharmaceutical packaging solutions, offering 100% recyclable aluminum pill bottles. The company is dedicated to providing environmentally-friendly options for pharmaceutical companies committed to reducing their ecological footprint and promoting a healthier planet for future generations.

Grand Rapids, MI

Based in Grand Rapids, MI, Packaging Compliance Labs provides comprehensive sterile packaging solutions for medical device manufacturers. They specialize in package testing, contract packaging, and packaging engineering services, ensuring critical validations and ISO 11607 compliance. The company is ISO 17025 and ISO 13485 accredited, offering in-house expertise.

Holland, OH

Based in Holland, OH, Plastic Technologies Inc. specializes in comprehensive plastic packaging solutions. They offer thermoform, flexible, hot-fill, and aseptic packaging, along with product design, development, and testing services. The company serves diverse industries, including Pharmaceutical and Medical, Food and Beverage, and Personal Care.

Fort Worth, TX

Based in Fort Worth, TX, Polymerall LLC manufactures custom printed and laminated flexible packaging. They provide a range of films, bags, and pouches, including specialized Easysnap single-dose packaging solutions. The company serves diverse markets such as food, pet food, and personal care, with capabilities well-suited for pharmaceutical applications.

Simi Valley, CA

Poly-Tainer, headquartered in Simi Valley, CA, specializes in manufacturing and decorating custom and stock plastic bottles. Utilizing PET, HDPE, LDPE, and PCR materials, the company provides packaging solutions for personal care, food and beverage, and healthcare sectors. They maintain a Drug Master File (DMF) for pharmaceutical packaging applications.

Janesville, WI

Based in Janesville, WI, Prent Corporation is a global leader specializing in thermoformed packaging trays. The company provides innovative packaging solutions primarily for medical devices and electronics, designing custom thermoformed products to meet the stringent requirements of sensitive industries.

San Diego, CA

Based in San Diego, CA, Print247 manufactures custom packaging solutions, including a full range of pharmaceutical products. They offer bespoke labels, auto-lock bottom boxes for syrups, and display boxes. The company also provides custom Mylar bags and protective packaging designed to enhance product appeal.

Atlanta, GA

Based in Atlanta, GA, Printpack manufactures flexible and specialty rigid packaging solutions. Printpack Medical provides a full line of medical packaging products, including bags, forming films, laminations, and pouches. They offer advanced printing, sustainable options, and extensive manufacturing and converting capabilities.

Anaheim, CA

ProAmpac manufactures flexible packaging solutions, including medical device packaging for aseptic handling. Based in Anaheim, CA, they offer custom prototypes, sustainable options like ProActive Recyclable films and fiber products, and leverage advanced material science. They provide creative packaging to diverse global markets.

Islandia, NY

Based in Islandia, NY, Printex Transparent Packaging specializes in custom transparent packaging for diverse markets. The company provides design services, silk screen printing, foil stamping, plastic die cutting, and prototyping. They serve industries like pharmaceuticals, health & beauty, food & beverage, and wine & spirits packaging needs.

Based in Wayne, NJ, Reed-Lane, Inc. is a pharmaceutical contract packager operating since 1959. The company specializes in blister packaging, bottling, pouching, and convenience vial filling. Services include secondary packaging, cold chain storage, serialization, and kitting, utilizing an FDA-inspected production facility.

Rosenberg, TX

SCHC, located in Rosenberg, TX, specializes in custom label pharmaceutical packaging, providing high-quality packaging materials and custom labeling for wholesale clients. With a 100,000 sq ft warehouse, the company also offers custom corrugated boxes for branding and includes drayage services for efficient logistics.

Macungie, PA

Sharp Services, LLC provides commercial packaging for pharmaceutical injectables and sterile drug products from its GMP sites in the US. They deliver innovative primary and secondary packaging solutions, including assembly, labeling, and comprehensive packaging within cold chain and controlled environments for clinical and commercial needs.

Kingsville, TX

Sofrigam specializes in providing self-contained active and passive cold chain packaging solutions for the pharmaceutical, biotech, and life-sciences industries. Their GDP-compliant packaging ensures temperature-sensitive products maintain integrity during transport, mitigating damage from cold chain ruptures. They focus on delivering greener and more reliable logistics for medicines.

Fremont, CA

Based in Fremont, CA, Spectrum Custom Packaging manufactures custom boxes with design, printing, and converting solutions. They serve the medical and pharmaceutical sectors, adhering to rigorous quality standards and operating procedures for regulatory compliance. The company creates packaging that meets the critical demands of the highly-regulated healthcare industry.

Cedar Park, TX

Texas Technologies offers specialized packaging solutions and materials for critical environments, serving the medical industry. They provide cleanroom and moisture barrier packaging, desiccants, and temperature-controlled shipping solutions. The company also supplies a range of industrial sealers and cleanroom consumables, supporting comprehensive packaging requirements for sensitive products.

Phoenix, AZ

Based in Phoenix, AZ, The Product Boxes manufactures custom packaging solutions. Specializing in pharma Gel packaging boxes for medicines, they offer various custom sizes and designs. The company focuses on delivering secure, tailored packaging options to meet the specific requirements of pharmaceutical clients.

Cincinnati, OH

Based in Cincinnati, OH, TPC Pack provides optimized packaging solutions and equipment with over 55 years of expertise. They specialize in cold chain and temperature-controlled packaging, offering gel packs, insulated shippers, and pouches to various industries requiring precise environmental control.

Arnold, MO

Based in Arnold, MO, VisiPak manufactures clear plastic packaging solutions including custom and stock blister packaging, clamshells, tubes, closures, and caps. Utilizing extrusion, thermoforming, injection molding, and vinyl dip molding processes, VisiPak provides transparent packaging products essential for pharmaceutical and other industrial applications.

Farmers Branch, TX

Based in Farmers Branch, TX, We Customize Boxes manufactures custom packaging solutions. They specialize in child-safe packaging, engineered for easy adult handling yet difficult for children to open. This expertise makes them a relevant supplier for pharmaceutical companies.

Atlanta, GA

Based in Atlanta, GA, Altium Packaging manufactures rigid plastic containers and closures. The company provides packaging solutions for diverse markets, including healthcare, offering containers for prescription, over-the-counter, and wellness products. Altium also serves food, beverage, and personal care sectors.

Aptar provides innovative drug delivery and precision dosing solutions for the pharmaceutical industry. The company develops best-in-class technologies for injectables, nasal sprays, and oral dosing, supporting product development from concept to commercialization. Aptar also serves beauty, food, and other consumer product markets.

CCL Healthcare specializes in sustainable pharmaceutical packaging solutions, manufacturing labels, literature, and cGMP folded cartons. The company provides secondary packaging within cGMP facilities, serving pharmaceutical, biotechnology, and medical device markets globally, backed by over 65 years of printing experience.

Durham, NC

Ernest Packaging Solutions provides comprehensive packaging solutions for industries such as pharmaceutical, medical, food, beverage, and cosmetics. The company focuses on creative thinking and foresight to solve business challenges, helping clients bring products to market and build their brands. They aim to deliver effective packaging solutions.

Graphic Packaging specializes in designing and manufacturing protective packaging solutions for various industries. The company provides child-resistant packaging, often utilized for pharmaceuticals, medical devices, and other non-food consumer products, ensuring safety for vulnerable consumers.

Clinton, TN

Tjoapack offers comprehensive contract packaging services for the pharmaceutical industry, aiming to enhance supply chain safety and reliability. They specialize in packaging solutions for oral solids, injectables, pre-filled syringes, pharmaceutical vials, and secondary packaging, including kitting, for various patient needs.

Philadelphia, PA

Based in Philadelphia, PA, Adare Pharma Solutions is a global CDMO offering comprehensive contract packaging services for solid-dose pharmaceuticals. They provide expert packaging, serialization, and global logistics support from facilities in the US and Europe. Adare also specializes in oral dosage form development and commercial manufacturing.

Cleveland, OH

Alpha Packaging Inc. manufactures high-quality plastic bottles and jars primarily for the pharmaceutical, nutraceutical, and personal care markets. Utilizing advanced blow molding and injection molding technologies, the company produces a diverse range of PET, HDPE, and PP containers from its multiple US-based facilities.

Palatine, IL

Based in Palatine, IL, Ashland Container provides custom pharmaceutical packaging solutions. They offer a comprehensive range of packaging products, including glass, plastic, and metal containers, along with caps, closures, sprays, and pumps. The company serves as a full-service packaging partner from design to delivery.

Comar is a contract manufacturing partner providing primary packaging and dispensing solutions for healthcare and wellness applications. They offer stock, made-to-order, and custom-designed packaging, transforming concepts into market-ready solutions for their clients.

Mountainside, NJ

Based in Mountainside, NJ, DCC Packaging offers comprehensive print and packaging solutions for the pharmaceutical and healthcare industries. With in-house manufacturing, the company delivers precise, compliant, and brand-consistent packaging, ensuring swift turnarounds, G7 certified color, and just-in-time delivery for clients.

Greenwich, CT

Dymapak specializes in innovative and patented child-resistant packaging solutions for businesses. Their product line includes visually appealing blisters, tins, bags, and boxes, engineered to preserve various products and protect consumers. They also provide comprehensive custom packaging services.

March Air Reserve Base, CA

E2Global, based in March Air Reserve Base, CA, manufactures a diverse range of packaging and consumables. They specialize in producing sterile and non-sterile cryogenic tubes and flocked specimen swabs, crucial for medical applications. The company also offers bottle, tube, tin, and pump manufacturing solutions.

Bedford Heights, OH

Based in Bedford Heights, OH, New AGE, Inc. provides custom and contract packaging services. They specialize in package design, tooling, die cuts, thermoformed clamshells, blister combos, and shrink wrapping. Serving various industries, the company also offers packaging containers and supplies.

Doylestown, PA

Oliver Design, a business unit of Oliver Healthcare Packaging, specializes in custom packaging solutions for large-molecule therapies, biologics, and medical devices. The company offers design, engineering, and commercial production services, providing robust and compliant packaging across various formats for the healthcare industry.

Grand Rapids, MI

Based in Grand Rapids, MI, Oliver Healthcare Packaging develops, designs, and manufactures flexible sterile barrier packaging. They serve the medical device, diagnostics, pharmaceutical, and biopharmaceutical markets, offering solutions like LumaPeel for pouching and high barrier protection for diagnostics.

Cross Plains, WI

Plastic Ingenuity is a custom thermoformer providing packaging solutions for the healthcare, food, and consumer goods industries. As the largest custom thermoformer in North America, the company operates seven strategic locations, offering experience and dedicated customer service for scaling product packaging.

Dallas, TX

Based in Dallas, TX, Plastiform Inc. specializes in custom plastic thermoformed packaging, offering blister packs, clamshells, and insert trays. They serve the medical (pharmaceutical), consumer goods, and food industries, providing solutions focused on product visibility, protection, and security. Their services also include product design and mold building.

Fort Worth, TX

Based in Fort Worth, TX, Platinum Press provides custom printed packaging solutions. They specialize in high-quality packaging for the pharmaceutical, healthcare, and medical device industries, also serving pet care and personal care sectors with their diverse offerings.

Grand Rapids, MI

Praxis Packaging provides primary and secondary contract packaging for OTC and Rx pharmaceutical products. Operating five FDA, DEA, and cGMP-compliant facilities in Michigan, New Jersey, and Florida, they specialize in solid dose bottling, blister packaging, liquid/cream/paste filling, secondary packaging, and DSCSA serialization.

Bolivar, OH

Primary Packaging Inc., based in Bolivar, OH, manufactures flexible primary packaging solutions such as films, bags, and pouches. They specialize in barrier and specialty films, offering converted packaging like stand-up pouches and rollstock. The company serves diverse sectors, including the medical and pharmaceutical industries, providing tailored packaging solutions.

Loves Park, IL

Based in Loves Park, IL, Rock Valley Packaging manufactures custom industrial boxes for sensitive medications and healthcare products. They produce rigid, folding carton, and corrugated packaging, along with custom inserts. The company also offers graphic design, prototyping, inventory management, and warehousing services.

Aurora, IL

Based in Aurora, IL, Shorr provides specialized medical packaging solutions, offering expertise in cleanroom, tamper-resistant, and temperature-control packaging. Their services ensure sterility, compliance, and product integrity for sensitive pharmaceutical goods throughout the supply chain, meeting critical industry demands.

Westwood, NJ

Sonic Packaging provides contract packaging and filling services tailored for the pharmaceutical industry. Based in Westwood, NJ, they are FDA-registered, DEA compliant for controlled substances, and ISO certified. The company offers innovative packaging solutions, guiding clients through the entire process from concept to market.

Spectrum Plastics provides sterile packaging solutions, including pouches, header bags, and lids crafted with DuPont™ Tyvek®. The company offers high-level protection for medical devices and other sensitive applications, leveraging extensive expertise in the medical device industry.

Arlington Heights, IL

Based in Arlington Heights, IL, ThermoSafe specializes in temperature-controlled packaging and cold chain solutions for life sciences and healthcare industries. The company offers innovative packaging, including cold shipping boxes, gel packs, and foam bricks, alongside custom engineering and thermal testing services, ensuring safe transport of pharmaceuticals, biologics, and vaccines.

AlphaMed Bottles Inc. manufactures essential packaging components, including bottles, caps, closures, and jars. The company prioritizes quality, integrity, and performance, delivering reliable and cost-effective container solutions. AlphaMed's products are well-suited for pharmaceutical and medical applications, ensuring secure and compliant product containment.

Amcor is a global leader in developing and producing premium, responsible medical and pharmaceutical packaging. They provide flexible and rigid packaging solutions for diverse industries, including food, beverage, and personal care. Amcor partners with clients worldwide to protect products, enhance brands, and optimize supply chains.

American Health Packaging specializes in customized pharmaceutical packaging solutions and comprehensive contract packaging services. The company manufactures serialized, barcoded unit-dose oral solids and liquids for hospitals and pharmacies. They focus on ensuring regulatory compliance, patient safety, and streamlining the pharmaceutical supply chain.

East Providence, RI

Clayens, headquartered in East Providence, RI, specializes in the manufacture of injectable drug delivery systems, including auto-injectors. The company provides expertise to pharmaceutical clients, offering critical components for various medical applications and ensuring high-quality packaging solutions for drug administration.

TOPPAN Packaging Solutions offers concept-to-completion thermoforming and flexible packaging. They specialize in sterile medical and pharmaceutical packaging, providing lightweight flexible options and durable thermoformed designs. Their customizable solutions ensure product protection and presentation, meeting high industry standards for secure and market-ready products.

El Segundo, CA

Based in El Segundo, CA, PakFactory specializes in manufacturing custom pharmaceutical packaging boxes and solutions. They offer folding cartons, rigid boxes, labels, and flexible packaging designed for the healthcare industry. With an emphasis on compliance, customization, and innovative design, PakFactory provides high-quality packaging to maximize product appeal and safety.

Westfield, MA

Perlen Packaging is an international group with US operations in Westfield, MA, specializing in film manufacturing and film coating. The company provides primary packaging solutions tailored for the pharmaceutical industry, ensuring product integrity and safety through advanced material science.

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How to Choose a Company

  • Verify their cGMP compliance history, specifically adherence to FDA 21 CFR Parts 210/211 for drugs, and their current FDA registration status. Request their audit reports, CAPA documentation, and a detailed outline of their Quality Management System (QMS).
  • Assess their serialization and traceability capabilities for DSCSA compliance. Confirm they have Level 3 (site-level) and Level 4 (enterprise-level) systems for unique product identification, aggregation, and can exchange data via EPCIS with your internal systems or CMOs.
  • If your product requires temperature control, demand evidence of validated cold chain logistics infrastructure, including temperature-mapped storage, qualified shipping solutions, and robust excursion management protocols for specific temperature ranges (e.g., 2-8°C, -20°C).
  • Confirm their specific expertise in your required packaging formats, such as blistering (thermoform vs. cold form), parenteral filling, bottling with Child-Resistant (CR) closures, unit dose strips, or medical device kitting. Ensure their equipment is validated for your primary container.
  • Scrutinize their process validation protocols (IQ/OQ/PQ) and their ability to support or conduct stability testing programs. A common red flag is a lack of clear methodology for how packaging materials and processes are validated to maintain drug product stability.
  • Investigate their regulatory inspection history, including any FDA 483 observations or warning letters. Understand their responsiveness to corrective actions and their proactive approach to evolving regulatory requirements, which indicates a mature quality culture.
  • For startups, evaluate their flexibility regarding minimum order quantities (MOQs) and willingness to support pilot runs. For established enterprises, assess their capacity redundancy, disaster recovery plans, and ability to scale up efficiently for product line extensions.

Frequently Asked Questions

What's the primary difference between a cGMP-compliant packaging supplier and a standard contract packager?

cGMP compliance isn't merely about good practices; it's a regulatory mandate (e.g., FDA 21 CFR Parts 210/211) requiring rigorous documentation, validation (IQ/OQ/PQ), strict change control, and a robust Quality Management System specific to pharmaceuticals. This ensures the product's safety, identity, strength, quality, and purity are consistently maintained. A standard packager lacks this in-depth regulatory framework and dedicated quality oversight for pharmaceuticals.

How do I evaluate a pharmaceutical packaging company's serialization capabilities for DSCSA compliance?

Look beyond basic barcode printing. Assess their Level 3 (site-level) and Level 4 (enterprise-level) serialization solutions, their ability to generate and manage unique product identifiers, aggregate units into bundles, cases, and pallets, and seamlessly exchange data with your CMOs and trade partners via EPCIS. Verify their integration experience with various platforms and the robustness of their audit trails for data integrity.

My product requires strict temperature control. What specific questions should I ask about a packaging supplier's cold chain logistics?

Inquire about their validated temperature-controlled storage (refrigerated, frozen) and controlled room temperature (CRT) environments, evidence of temperature mapping studies, alarm systems, backup power, and comprehensive excursion management procedures. Ask for proof of qualified shipping lanes, packaging components suitable for cold chain, and extensive experience with specific temperature ranges (e.g., 2-8°C, -20°C).

What should I look for in a supplier if my product needs Child-Resistant (CR) or Senior-Friendly (SF) packaging?

Verify their direct experience with designing, engineering, and testing CR/SF packaging, ensuring it meets consumer product safety commission (CPSC) requirements (e.g., 16 CFR Part 1700.20 for CR testing). Ask for examples of successfully launched CR/SF products, their in-house testing methodologies or third-party validation partners, and their ability to source specific CR/SF closures, blister films, or other specialized components.

How critical is stability testing support from a packaging partner?

Extremely critical. Packaging can significantly impact a drug product's long-term stability. A knowledgeable partner understands ICH stability protocols and can provide real-time data or integrate seamlessly with your existing stability program. They should advise on how different packaging materials and formats (e.g., barrier films, closures) might affect shelf life, especially for moisture-sensitive or light-sensitive formulations, and offer appropriate storage conditions and analytical support.

What red flags should I watch for when vetting new pharmaceutical packaging suppliers?

Be wary of suppliers offering significantly lower prices without clear justification, those with inconsistent or incomplete quality documentation (e.g., poorly organized batch records, missing CAPA logs), a history of frequent FDA 483 observations or warning letters, or an inability to clearly articulate their process validation or serialization strategy. A lack of specific experience with your drug product class or primary packaging format is also a major red flag.

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