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Medical Adhesive Manufacturers

Last updated: February 2026

This directory lists 62 medical adhesive manufacturers across the United States, from specialists in high-performance skin-contact adhesives for wearables to experts in implantable adhesive systems for surgical applications.

Buyers frequently grapple with ensuring adhesives maintain integrity post-sterilization (e.g., EtO, gamma irradiation), achieving reliable long-term adhesion on diverse biological and synthetic substrates, and securing comprehensive biocompatibility data (ISO 10993) crucial for regulatory submissions.

The landscape includes custom formulators developing novel hydrogels or acrylates, contract manufacturers integrating adhesive application into device assembly, and material suppliers offering off-the-shelf medical-grade tapes or bulk adhesives. Distinguishing factors often lie in their R&D capabilities, cleanroom manufacturing environments, and specific regulatory expertise.

To engage effectively, buyers should arrive with detailed application requirements, target performance specifications for tack, peel, and shear, expected sterilization methods, and a clear understanding of their device's regulatory classification. Suppliers, in turn, expect comprehensive data on substrates, environmental exposure, and anticipated shelf-life to propose suitable adhesive chemistries.

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Company Directory

62 companies nationwide

Sunnyvale, CA

Based in Sunnyvale, CA, Ad-Surgical specializes in manufacturing next-generation topical skin adhesives and hemostats for the global healthcare market. Their product line features GLUSEAL Topical Skin Adhesive, a clear liquid bandage designed to protect minor cuts, scrapes, burns, and skin irritations from infection.

Adchem, through its Polyken brand, specializes in manufacturing highly engineered pressure-sensitive adhesive tape solutions. These innovative products are developed for medical original equipment manufacturers (OEMs) and converters, providing extensive and specialized adhesive technologies for diverse healthcare applications.

Alachua, FL

Amend Surgical manufactures biocompatible hydrogel and chitosan-based medical glues. Their innovative adhesives provide strong adhesion on wet, uneven, and mechanically challenging surfaces. Offerings include resorbable and non-resorbable barriers for applications such as oral cavity procedures and reconnecting peripheral nerves, minimizing the need for sutures.

Anaheim, CA

Based in Anaheim, CA, Amparo Medical Technologies formulates and manufactures custom hydrocolloid medical-grade adhesives. This ISO 13485 certified company produces master rolls for applications like wound care, ostomy, device attachment, drug delivery, and cosmetics, offering tailored performance and components.

ASO Corp is a manufacturing partner for medical devices and consumer self-care products, leveraging in-house acrylic adhesive coating capabilities. The company provides R&D, design, regulatory compliance, and manufacturing solutions to produce products requiring optimal adhesion for various medical applications.

Colorado Springs, CO

Aspire Biotech Inc. specializes in providing high-purity cyanoacrylates, essential components for tissue adhesives. They offer capabilities to supply highly pure butyl and octyl cyanoacrylate, critical for medical adhesive manufacturing. Based in Colorado Springs, CO, the company directly supports the industry with specialized chemical supplies.

Irwindale, CA

Based in Irwindale, CA, Cactus Tape engineers reliable pressure-sensitive adhesive tapes primarily for medical and healthcare applications. They specialize in custom diagnostic tapes, providing solutions designed for faster production, cleaner bonds, and enhanced design flexibility to solve specific application challenges.

Atlanta, GA

Chemence specializes in creating solutions through specialty chemicals, manufacturing a range of adhesives and sealants. The company provides topical skin adhesives for the medical market, holding FDA clearances and EU MDR/MDSAP certifications for its products. Chemence has corporate offices near Atlanta, Georgia, serving diverse industries.

Oceanside, CA

Custom Converting, Inc. is an ISO 9001:2015 and FDA-registered contract manufacturer based in Oceanside, CA. They provide custom adhesive coating, precision die cutting, and converting services for the medical device, topical patch, and medical testing industries, manufacturing to cGMP specifications.

Tallmadge, OH

Based in Tallmadge, OH, DermaMed manufactures pressure-sensitive adhesive medical tapes and coated materials. They specialize in solutions for wound care, surgical disposables, and wearable devices, offering product customization and testing. The ISO 13485 certified company leverages advanced technologies to provide specialized adhesive materials for healthcare applications.

Huntington Park, CA

Based in Huntington Park, CA, DMG Medical Supply manufactures sterile adhesive wound closure strips from flexible non-woven material for secure wound closure. The company also provides a range of medical supplies, including durable medical equipment, mobility scooters, and adult briefs, serving commercial customers.

Factor II, Inc. specializes in the art, science, and technology of silicones and prosthetics, having operated since 1978. The company is a comprehensive supplier of medical, prosthetic, and three-dimensional make-up supplies, offering a range of adhesive products, cartridge systems, and silicone materials for advanced applications.

Germantown, WI

Based in Germantown, WI, GDI Adhesives specializes in custom manufacturing of pressure-sensitive adhesive solutions for various industrial applications. The company develops silicone-based PSAs, suitable for sensitive skin applications and long-term wear, leveraging patented technology and extensive industry experience.

Plainsboro, NJ

Based in Plainsboro, NJ, Gleicher Manufacturing is a converting partner that fabricates transparent polyurethane films featuring skin-friendly adhesives. These materials are designed for wound care, offering water-resistant properties and suitability for both short-term and long-term wear in medical applications.

Sanford, FL

Based in Sanford, FL, Hernon Manufacturing specializes in advanced adhesive solutions. They produce ultraviolet light curable adhesives designed to form strong bonds on metals, plastics, and other materials. The company's offerings include specialized industrial adhesives suitable for various common medical applications and manufacturing requirements.

Buena Park, CA

Based in Buena Park, CA, Hi-Tech Medical Products specializes in cleanroom converting and precision rotary die cutting for complex medical components. They manufacture adhesive-based products, including transdermal patches, stick-to-skin device attachments, and catheter securement systems. The company is ISO 13485:2016 certified.

Spartanburg, SC

Based in Spartanburg, SC, Incure Lab manufactures adhesive systems engineered for demanding applications. They develop specialized adhesives that meet stringent biocompatibility standards, including USP Class VI and ISO 10993, serving professionals who require certified solutions for medical device manufacturing.

Houston, TX

Kuraray America, Inc., headquartered in Houston, TX, is a manufacturer of medical adhesives for dental applications. The company specializes in advanced bonding agents and adhesive systems, offering dual-cure, light and self-cure, and chemical-cure technologies. They also produce a broad portfolio of specialty polymers and chemicals.

Based in New York, NY, Kuraray Dental manufactures dental supplies and bonding solutions for dentists and dental technicians. The company provides a range of dental adhesives used in prosthetic and restorative dentistry, trusted by professionals globally.

Clifton, NJ

Based in Clifton, NJ, Lamart Corporation designs and manufactures custom engineered coated films, fabrics, and foils for the medical market. They provide a full line of skin-friendly and aggressive adhesives for drug delivery systems, medical device components, and wound care products, holding ISO 13485 certification.

Avery Dennison Medical develops and manufactures innovative medical adhesive solutions for wound and skin care applications. With over 45 years of expertise, they collaborate with medical device manufacturers to create high-performance and reliable products.

Elk Grove Village, IL

Based in Elk Grove Village, IL, Meridian Adhesives Group manufactures innovative adhesive solutions for diverse industries, including medical. They offer EPO-TEK® certified medical epoxies and adhesives for implants, diagnostics, and tools, ensuring biocompatibility and reliability in critical applications.

Valencia, CA

Based in Valencia, CA, Neotech Products manufactures medical devices utilizing specialized adhesive technologies. They produce SoftSil Silicone Adhesive Patches for skin protection and NeoLead ECG Electrodes featuring hydrocolloid borders. The company focuses on developing skin-friendly, secure, and reliable adhesive solutions for various medical applications.

Hayward, CA

Pacific Die Cut Industries provides custom die cut solutions and converted products for various industries, including medical. They specialize in die-cut products and services for transdermal delivery, nutraceutical therapy, and arthritic pain relief applications, working with adhesive-backed materials.

Wabasha, MN

Pepin Manufacturing, Inc. provides contract converting and fabrication services, delivering precision-engineered solutions for diverse industries. The company specializes in rotary and flatbed die-cutting, precision cutting, and custom electrode manufacturing for electrotherapy applications. They offer quality stick-to-skin adhesives and high-performance components.

Based in Pottstown, PA, Permabond is a manufacturer, formulator, and innovator of industrial adhesives, including a specialized Medical Device Adhesive line. The company provides expert technical assistance, product recommendations, and custom formulations for diverse industries worldwide, offering short lead times and low minimum order quantities.

Cherryville, NC

Based in Cherryville, NC, Pocono Pharmaceutical is a US contract manufacturer specializing in transdermal delivery systems, topical patches, and kinesiology tapes. They provide scalable, cGMP-compliant manufacturing solutions for matrix-coated products, topicals, and cosmetics, serving worldwide markets since 2004.

Warwick, RI

Based in Warwick, RI, PolarSeal is a contract manufacturer specializing in the design, development, and production of advanced medical adhesive systems. The company provides high-quality, innovative stick-to-skin solutions for wearable medical devices, wound care, and drug delivery systems for various medical and industrial applications.

Polymer Science, Inc. is a US-based manufacturer specializing in adhesives, tapes, and coatings for diverse industries. The company provides medical-grade adhesives for medical devices and direct skin contact applications, along with materials for aerospace, defense, and electronics. They deliver tailor-made designs to meet specific application requirements globally.

Tempe, AZ

Based in Tempe, AZ, Precision Converting offers contract manufacturing services, specializing in precision die-cutting, slitting, and laminating of medical-grade adhesives and flexible materials. Operating in ISO Class 7 cleanrooms, they produce critical components for medical devices and diagnostic applications.

Knoxville, TN

Based in Knoxville, TN, Scapa Healthcare designs, develops, and manufactures skin contact solutions. The company provides innovative skin-friendly fixation and topical solutions for advanced wound care, consumer wellness, and medical device fixation applications, serving healthcare and consumer companies.

Woodland, CA

Based in Woodland, CA, Skinister manufactures high-quality medical adhesives. Formulated with silicone, their specialized adhesive is suitable for diverse applications including medical uses, visual effects, and cosplay. The company provides direct access to its innovative silicone-based adhesive solutions for specialized consumer and professional needs.

Woodland, CA

Skinister Medical specializes in providing high-quality silicone-based medical adhesives and removers, along with silicone prosthetics. Their products are designed for reliable performance and excellent adhesion, serving the ostomy and mastectomy communities with ease of use.

Smith+Nephew is a medical technology company specializing in orthopaedics, sports medicine, ENT, and advanced wound management. They develop solutions for the repair, regeneration, and replacement of soft and hard tissue, likely manufacturing or utilizing various medical adhesive technologies for wound closure and tissue repair.

Saint Paul, MN

Based in Saint Paul, MN, Solventum, spun off from 3M's healthcare business, offers medical device manufacturing expertise and product solutions. They cater to applications like medical wearables, transdermal patches, diagnostics, and microfluidics, leveraging a rich history in healthcare to deliver critical components and innovation.

Dallas, TX

Based in Dallas, TX, Strukmyer is a contract manufacturing operation specializing in custom development and manufacturing for advanced wound care. The company provides a range of services, including die-cutting and sterile packaging, offering comprehensive solutions for medical product development and production.

Encinitas, CA

Tokuyama Dental America Inc., based in Encinitas, CA, manufactures advanced dental products through integrated R&D and manufacturing. Specializing in chemical technology and composite development, the company produces high-quality dental adhesives, including innovative self-cure universal bonds for various dental substrates and applications.

Indianapolis, IN

Based in Indianapolis, IN, Aurorium manufactures specialty ingredients and performance-enhancing materials. They offer Biothane™ Polyurethane Sealant Systems, specifically formulated for use as adhesives and sealants in medical devices. Aurorium supports the healthcare industry by providing materials engineered to meet rigorous demands and empower drug efficacy.

BioDevek, based in Allston, MA, specializes in developing a fully biodegradable and highly biocompatible adhesive material platform. Their innovative technology aims to overcome challenges with existing commercial adhesives, suggesting a focus on advanced medical applications.

St. Paul, MN

Innovize provides turnkey process development and production services, converting adhesives, tapes, films, hydrogel, and hydrocolloid into medical products for skin contact applications. The company offers sourcing and manufacturing capabilities, operating under an ISO 13485:2016 certified quality management system.

Medtronic manufactures advanced medical adhesives for surgical applications. Their product, LiquiBand® Exceed™, is a 2-octyl-cyanoacrylate topical skin adhesive designed for closing medium to long surgical incisions. They focus on providing innovative solutions for wound closure in healthcare settings.

Based in Glen Rock, PA, ARx Pharma manufactures flexible, patient-friendly adhesive solutions for oral thin film and transdermal drug delivery systems. Utilizing FDA-approved materials, they operate FDA-registered cGMP facilities, offering comprehensive process development and commercial manufacturing for pharmaceutical partners.

Deerfield, IL

Baxter International is a global healthcare company providing essential medical products. They are a direct manufacturer of medical adhesives, including their Tisseel fibrin sealant. Surgeons rely on this proven product for clinical safety and efficacy as an adjunct to hemostasis in various surgical procedures.

Schaumburg, IL

Based in Schaumburg, IL, BISCO Inc. specializes in the manufacturing of light-cured, universal dental adhesives. The company provides a range of bonding agents, including products like All-Bond Universal, designed for dental professionals. BISCO focuses on developing advanced adhesive solutions for the oral health industry.

Wilsonville, OR

Based in Wilsonville, OR, Cleanroom Tape operates a dedicated Clean Room manufacturing facility. The company specializes in producing particle-free and residue-free adhesive tapes, including specialized Medical & Pharmaceutical Tape. They offer a diverse range of adhesive solutions for various industrial and critical application sectors.

Chicago, IL

Cosmedent, based in Chicago, IL, manufactures advanced dental adhesive systems for dental professionals. The company specializes in products like primers and unfilled resins for light-cure situations, supporting dental restorative procedures. Cosmedent provides essential materials for effective patient care.

Hayward, CA

Delphon develops innovative materials and processes for the medical device industry, specializing in solutions like biocompatible carriers, antimicrobial coatings, and adhesives. Leveraging expertise in polymers, the company supports the safe handling and shipping of leading-edge technologies with its specialized product lines from its facility in Hayward, CA.

Flexcon Company, Inc. manufactures medical adhesive products, including flexible over-tapes, medical adhesive tape, and double-face films. They specialize in adhesives for wearable devices and bonding medical devices to the body, serving various medical applications.

Eden Prairie, MN

Based in Eden Prairie, MN, Adhesive Systems Inc (ASI) manufactures medical-grade cyanoacrylate super glues, such as their MG Series, engineered for fast and permanent bonding. They also offer a comprehensive selection of industrial-grade structural adhesives, epoxies, MMAs, and various adhesive application equipment.

Bentonville, AR

Based in Bentonville, AR, Henkel develops flexible adhesive solutions specifically for medical devices. The company's products support digital health care initiatives, contributing to improved patient care and healing outcomes. Henkel operates extensively across over 70 sites in North America.

Master Bond formulates and manufactures high-performance adhesives, sealants, and coatings for various industries. Specializing in biocompatible solutions, their products meet USP Class VI and ISO 10993-5 standards for medical device assembly. They offer custom formulations and technical support, with products freshly made-to-order from their USA facility.

Waterford, NY

Momentive manufactures advanced silicone pressure-sensitive adhesives (PSAs) known for high-performance bonding, clean removal, and durability. These specialized adhesives are engineered for critical medical device applications and advanced wound care solutions. Based in Waterford, NY, Momentive operates multiple US manufacturing facilities, serving the B2B healthcare industry.

Lake Forest, CA

Based in Lake Forest, CA, R&D Medical Products specializes in manufacturing hydrogels and skin adhesive wearables for diverse medical applications. They are a transdermal patch manufacturer, providing custom solutions for industries including wound care, orthopedic care, pharmaceutical, and telemedicine.

3M is a global science and manufacturing company developing diverse technologies and products. They produce a wide array of advanced adhesives, including cyanoacrylates, for various industrial and commercial applications. 3M directly provides adhesive solutions for sectors including healthcare and medical device manufacturing.

Pleasanton, CA

Boyd Corporation specializes in designing and manufacturing medical-grade adhesive solutions and assemblies. They provide custom, multi-layer adhesive products including films, foams, and gels for advanced medical devices, diagnostics, and wearable technologies. Their solutions prioritize secure and gentle skin adhesion, moisture management, and infection protection for healthcare applications.

Lompoc, CA

Based in Lompoc, CA, DenMat is a US manufacturer operating a 100,000 square foot facility. The company specializes in professional dental products, directly providing a range of dental adhesives, bonding agents, and cements for clinicians and dental practices.

Milwaukee, WI

Lohmann provides integrated adhesive solutions for medical wearables, specializing in biocompatible and skin-friendly adhesives for both short- and long-term wear. The company offers inhouse coating, converting, and die-cutting services, developing innovative adhesive tape ranges for diverse market demands.

Stow, OH

Mactac manufactures a comprehensive range of adhesive solutions, including medical tapes, film tapes, foam tapes, non-woven tapes, and transparent film dressings like Visoderm. They offer transfer adhesives and hot melt adhesives, serving diverse industrial and medical applications. The company focuses on providing reliable, high-performance adhesive materials for various products.

Columbus, OH

Based in Columbus, OH, Matrix Adhesives Group provides adhesive and sealant solutions. They offer reliable private label and contract manufacturing, developing custom innovative solutions. Their expertise includes biocompatible sealing and bonding solutions specifically for medical devices and laboratory equipment.

Northfield, IL

Medline provides OptiClose™, a portfolio of surgical glues engineered for fast, secure wound closure. These medical adhesives enhance operating room efficiency and support positive patient outcomes. As a prominent healthcare manufacturer, Medline develops and supplies a comprehensive array of medical products and solutions for various clinical settings.

Romeoville, IL

Based in Romeoville, IL, Plitek is a custom manufacturer and converter of performance films and specialty materials. They provide comprehensive services including die-cutting, slitting, laminating, and multi-layer coating. Utilizing ISO Class 7 and 8 cleanrooms, Plitek manufactures a variety of medical and wound care products, such as dressings, medical tapes, and transdermal patches.

RevBio Inc. specializes in TETRANITE®, a groundbreaking synthetic bone adhesive inspired by the sandcastle worm. This innovative biomaterial is effective for bone-to-bone and bone-to-metal wet field applications. TETRANITE® offers rapid mechanical stability and controlled biodegradability, aiming to transform bone repair for medical professionals.

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How to Choose a Company

  • Verify the manufacturer's specific expertise in your target adhesive chemistry, such as UV-curable acrylates for rapid bonding or silicone pressure-sensitive adhesives (PSAs) for delicate skin contact, ensuring they have proven formulations for your application.
  • Demand documented evidence of ISO 10993 biocompatibility testing for all proposed materials intended for direct or indirect patient contact, especially for Class II or Class III devices where regulatory scrutiny is highest.
  • Assess their capabilities for post-processing validation, particularly their experience in maintaining adhesive integrity and performance after common sterilization methods like Ethylene Oxide (EtO), gamma irradiation, or e-beam.
  • Confirm their quality management system is certified to ISO 13485, demonstrating adherence to medical device specific regulatory requirements, and inquire about their FDA 21 CFR Part 820 compliance history and audit readiness.
  • Red Flag: Be wary of suppliers who offer "medical-grade" adhesives without readily available certificates of analysis (CoAs) or detailed material datasheets explicitly referencing medical compliance, as this often indicates unvalidated claims or a lack of proper traceability.
  • For startup innovators, prioritize manufacturers willing to engage in smaller batch runs for prototyping and design verification, while enterprise buyers should focus on scalability, global supply chain robustness, and established regulatory affairs support for complex submissions.

Frequently Asked Questions

What specific biocompatibility testing (ISO 10993) should I request for a new skin-contact medical adhesive?

For any adhesive making direct or indirect contact with skin, you must demand at least ISO 10993-5 (cytotoxicity), ISO 10993-10 (irritation and sensitization), and often ISO 10993-11 (systemic toxicity) data. The exact battery of tests depends on the duration and nature of patient contact, becoming more extensive for long-term or invasive applications.

How do I ensure a medical adhesive maintains its performance after sterilization?

A critical step is to validate the adhesive's key performance metrics—such as peel strength, tack, and shear strength—after exposure to your chosen sterilization method (e.g., Ethylene Oxide, gamma irradiation, autoclave). This often requires accelerated aging studies combined with post-sterilization performance testing to predict long-term stability and ensure no degradation occurs.

What's the difference between an acrylate and a silicone medical adhesive, and when should I use each?

Acrylates typically offer strong, aggressive adhesion and excellent shear strength, often used in transdermal patches or rigid device assembly where durable, long-lasting bonds are needed. Silicones, conversely, are known for their gentle, repositionable adhesion, excellent breathability, and inertness, making them ideal for delicate skin applications like wound care, wearable sensors, or ostomy devices where minimizing trauma upon removal is key.

What documentation should a medical adhesive manufacturer provide for regulatory submissions (e.g., FDA 510(k))?

Expect comprehensive documentation including Certificates of Analysis (CoAs) for each batch, Material Safety Data Sheets (MSDS/SDS), detailed technical data sheets with performance metrics, ISO 10993 biocompatibility reports, statements of compliance (e.g., RoHS, REACH if applicable), and critically, either a Master File or a Letter of Authorization (LoA) for proprietary formulations used in your device.

Is it safe to assume an adhesive marketed as "medical-grade" is suitable for my device without further qualification?

Absolutely not. 'Medical-grade' is a broad, often self-declared term. You must still fully qualify the specific adhesive for your device, your application, and your sterilization method. This includes verifying its specific biocompatibility, adhesion performance on your chosen substrates, long-term stability under expected conditions, and regulatory compliance directly relevant to your product's classification and market. Always ask for specific data and certifications relevant to your use case.

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