Bone Graft Manufacturers

Berkeley Biologics LLC operates as a contract manufacturer, providing comprehensive turnkey services for partners. The company specializes in offering private-label allograft opportunities, including custom solutions for specialized tissue processing and manufacturing within the biologics sector.

Based in Santa Cruz, CA, Dimensional Bioceramics, LLC specializes in the development and manufacturing of bioceramic medical devices. The company produces DB-EZ Bone Void Filler, an FDA 510(k)-cleared product designed for orthopedic applications and bone void filling procedures.

Based in San Antonio, TX, Alamo Biologics operates as a full-service tissue bank. The company provides high-quality allografts and biologics, specializing in the processing, storage, and distribution of donor tissue. Their mission focuses on honoring tissue donation and providing healing allografts to recipients.

Based in Centennial, CO, AlloSource is a human tissue provider specializing in innovative allografts. They create dermis, cartilage, tendon, fascia, bone, and amnion products, including bone and amnion allografts used in various spine procedures.

Anika Therapeutics, Inc. specializes in hyaluronic acid-driven regenerative solutions, manufacturing medical devices like Tactoset. This biocompatible, calcium phosphate injectable bone substitute is utilized for treating insufficiency fractures and augmenting hardware. The company also offers the Integrity Implant System for tendon repair applications.

ATEC Spine, Inc. develops and manufactures medical devices for spine surgery. Their product portfolio includes porous titanium interbody spacers and AlphaGRAFT DBM Fibers, a demineralized bone matrix (DBM) product offering an osteoconductive scaffold made of 100% demineralized fibers for orthopedic procedures.

Baxter is a global healthcare company that develops, manufactures, and markets a broad portfolio of medical products. They directly provide bone graft manufacturing services, including their U.S. FDA-cleared synthetic bone graft substitute, Actifuse Flow. Baxter serves healthcare providers and patients with innovative solutions.

Berkeley Biologics is a contract manufacturer of orthopedic and spinal allografts. Based in Richmond, CA, they offer turnkey services and private-label opportunities, supporting custom product development, processing, and distribution. The company operates an FDA-registered, AATB-accredited facility, providing comprehensive solutions for the biologics industry.

Based in Cordova, TN, Bioventus delivers innovative surgical orthobiologics and active healing solutions for orthopedic care. The company provides a comprehensive portfolio of clinically efficacious and cost-effective biologic therapies for patients, physicians, and payers.

Bioventus Surgical manufactures a comprehensive portfolio of surgical orthobiologics, providing a variety of bone graft solutions for surgeons and patients. They focus on advancing orthobiologic science and surgical performance, delivering clinically efficacious and cost-effective products like OSTEOAMP SELECT Flowable, a 100% allograft.

Based in San Antonio, TX, Bone Bank Allografts provides regenerative medicine technologies and allograft tissue products. The company processes tissue donations, offering sterile bone and soft tissue allografts, including demineralized bone matrix, cortical bone fibers, and specialty custom products. They serve the surgical community with solutions for healing and recovery.

Avtec Surgical, based in Mount Pleasant, SC, specializes in manufacturing advanced bone graft solutions. The company produces Demineralized Bone Matrix (DBM) Crunch, a pure bone tissue product with a larger particulate size. Their DBM contains no carrier or filler, providing an effective option for bone regeneration procedures.

Cerapedics manufactures advanced bone graft solutions and bone growth accelerators. Their portfolio includes FDA-approved PearlMatrix™ P-15 Peptide Enhanced Bone Graft for lumbar spine fusion and i-FACTOR® P-15 Peptide Enhanced Bone Graft for ACDF. The company emphasizes rigorous clinical evidence to advance spine surgery.

Based in Cypress, CA, Dentium USA manufactures advanced synthetic osteoconductive bone graft materials. Their Osteon III product offers excellent wettability and a porous structure, designed to facilitate bone regeneration. These solutions improve patient outcomes for immediate implantation and other sophisticated dental applications, supporting optimal treatment.

Based in Ridgefield Park, NJ, Hiossen Implant USA manufactures dental implants, prosthetic kits, and various surgical tools. The company also produces A-Graft Deproteinized Bovine Bone (DBB) bone graft materials, supplying essential products for oral and maxillofacial surgical procedures.

Based in Princeton, NJ, Geistlich Pharma North America Inc. specializes in manufacturing regenerative medical devices and biomaterials for bone, cartilage, and tissue regeneration. The company provides naturally sourced biomaterials for predictable clinical outcomes, primarily serving dental, surgical, and sports medicine professionals with advanced regenerative solutions.

Based in Princeton, NJ, Geistlich develops and manufactures biomaterial solutions for dental professionals. The company specializes in regenerative dentistry products, including bone substitutes like Bio-Oss® and collagen membranes such as Bio-Gide®, used for guided bone and tissue regeneration.

Glidewell Dental, based in Newport Beach, CA, specializes in advanced dental solutions. They offer digital dentistry, restorative solutions, implants, and biologics, including bone allografts. The company provides in-office technologies for designing, milling, and delivering dental restorations, emphasizing their manufacturing capabilities for various dental products.

Based in Irvine, CA, Glidewell Direct manufactures high-quality regenerative products for various grafting indications. The company also produces a range of dental solutions including BruxZir Solid Zirconia and Glidewell HT Implants from titanium alloy, serving clinicians globally.

Globus Medical, based in Carrollton, OH, manufactures a comprehensive portfolio of biologics for musculoskeletal conditions. Their offerings include cellular allografts, synthetic bone void fillers, and demineralized bone products. The company develops integrated solutions and enabling technologies to improve patient care.

Based in Chatsworth, CA, Hans Medical provides demineralized bone fibers, branded as AlloGraft Plus, for osteoinduction and osteoconduction. These bone graft products feature a unique fibrous network engineered for excellent osteoconductive potential and retention properties, serving various medical applications.

Based in Oceanside, CA, HDA Technology provides custom medical device development and manufacturing, specializing in orthopedic and spinal applications. Services include product design, prototyping, CNC machining, injection molding, cleanroom assembly, sterilization, and packaging solutions for various medical devices.

Based in Old Bethpage, NY, HIMED manufactures medical-grade calcium phosphate powders, granules, and hydroxyapatite. These biomaterials are supplied to medical device manufacturers for applications like dental implants, bone fillers, and synthetic bone grafts. HIMED enhances designs with osseoconductive properties for various medical applications.

Based in Thousand Oaks, CA, Implant Direct manufactures dental implant solutions. The company provides diverse implant systems and biomaterials, including DirectGen™ DBM Putty for bone grafting in dental procedures. They focus on delivering high-quality products to clinicians, enhancing patient access to predictable outcomes.

Based in Anaheim, CA, Induce Biologics Inc. develops and manufactures novel osteobiologic products. The company leverages Natural Matrix Protein (NMP) technology to create bioimplants for orthopedic, dental, and spinal applications, effectively stimulating natural bone regeneration processes for enhanced healing.

Based in San Leandro, CA, JRF Ortho is a specialized company and supplier of fresh osteochondral allografts. They have provided over 20,000 fresh OCA grafts since 2006, focusing on cartilage restoration and advancing orthopedic techniques.

Keystone Dental Group offers dental solutions, specializing in tissue regeneration and biomaterials. The company provides a range of products, including bone graft materials such as DynaGraft-D Putty and SG Granule, for dental professionals. It supports various dental applications through its online eShop.

Based in New Orleans, LA, Kinamed manufactures advanced medical devices for orthopedic and neurosurgical applications. Their product portfolio includes OsteoRepair, a next-generation calcium phosphate cement for bone repair, alongside bone preparation systems, patient-matched replacement devices, and specialized fixation products for surgical procedures.

Nobel Biocare manufactures xenogenic bone substitutes for guided bone regeneration (GBR) and guided tissue regeneration (GTR). Their regenerative portfolio supports dental implant procedures, including solutions for site preparation and innovative restorative designs. The company provides digital workflows to enhance esthetic zone and full-arch treatments for clinicians.

NovaBone is a biotechnology company specializing in developing and manufacturing advanced biomaterials. They focus on products for bone and soft tissue regeneration, catering to the specialized needs of dental and orthopedic surgeons. Their offerings include bone grafts, dental putties, and wound matrices.

Based in San Diego, California, NuVasive manufactures advanced biologics, including allogeneic bone graft substitutes and extenders for spinal procedures. Their portfolio also features synthetic ceramic bone graft substitutes, contributing to innovative orthopedic solutions. The company is currently transitioning its operations to Globus Medical.

Based in San Antonio, TX, NVISION Bio Medical Technologies is a medical device and biologics company. It provides surgeons with innovative implants and biologics designed to simplify and improve surgical procedures. The company offers products for spine and extremities, committed to high-quality orthopedic solutions for treatment and diagnosis.

Based in Warsaw, IN, OrthoPediatrics Corp. designs and manufactures specialized orthopedic products for pediatric patients. Their comprehensive offerings include solutions for trauma, deformity correction, and external fixation. The company also produces CERAMENT BONE VOID FILLER, a synthetic bone graft substitute for bone regeneration in children.

Based in Woburn, MA, OSSIO Inc manufactures bio-integrative orthopedic implants using its proprietary OSSIO fiber® material. These implants, composed of natural bone minerals, are designed to securely fixate, fully integrate into native bone, and restore strength without permanent metal hardware.

Based in Leander, TX, Parametrics Medical provides a comprehensive portfolio of biologic solutions, including allograft tissue and biologic implants. Specializing in regenerative medicine, the company serves sports medicine, wound care, and various orthopedic specialties such as spine, extremities, and oral surgery. They hold tissue processing credentials for advanced patient care.

Pinnacle Transplant Technologies, based in Phoenix, AZ, manufactures high-quality allograft implants. They produce precision-machined grafts, demineralized bone matrix/fibers (DBM/DBF), and allograft chips. These solutions serve Spine, Sports Medicine, Orthopedics, Trauma, Dental, and Wound Care, with tissue prepared through extensive testing and validated sterilization processes.

restor3d manufactures personalized, 3D-printed orthopedic implants for reconstructive surgery. They leverage proprietary osseointegrative materials and AI-based design automation to create patient-specific solutions. These implants are tailored to individual anatomies, optimizing surgical outcomes and facilitating bone integration.

Based in Hackensack, NJ, Royal Biologics Inc. develops orthobiologic and life science solutions for enhancing healing. The company focuses on autologous and live cellular therapies to address musculoskeletal and regenerative medicine challenges through a comprehensive product portfolio. Offerings include surgical products and wound care solutions.

Based in Fullerton, CA, SigmaGraft Biomaterials, Inc. manufactures high-quality biomaterials for dental and orthopedic surgeries. They specialize in innovative bone substitutes, allografts, xenografts, and resorbable membranes used for bone and tissue regeneration. The company focuses on research, development, and production of these products.

SolcoAmerica manufactures synthetic bone grafts, including synthetic strips made from purified fibrillar collagen and resorbable ceramic granules. These grafts are designed to be resorbed and replaced by natural bone. The company offers biologics for cervical, thoracolumbar, and kyphoplasty applications.

Based in Boca Raton, FL, SurGenTec, LLC is a medical device company focused on products for spine and orthopedic surgeries. They manufacture bone graft materials, including NanoPutty, HydroPutty, and HydroFiber, and develop innovative bone graft delivery devices. The company aims to enhance patient quality of life.

Surgical Esthetics Biomedical Technologies, Inc. manufactures and supplies bone graft and allograft products, alongside other dental regenerative biomaterials. Their offerings include membranes, collagen, sutures, and implant instruments. Serving general dentists and specialists, the company focuses on high-quality products for optimal patient healing.

Ultradent Products manufactures a diverse range of dental solutions, including OsteoGen® Bone Grafting Plugs, directly serving the bone graft sector. Based in South Jordan, UT, their product line also features Opalescence teeth whitening systems, etchants, fluoride varnish, and universal bond adhesives for improving global oral health.

Based in Laguna Hills, CA, Unicare Biomedical Inc. designs, develops, manufactures, and distributes innovative wound care and tissue regeneration solutions. The company provides bone grafts, membranes, and hemostats for dental and orthopedic professionals, adhering to ISO 13485 quality standards.

Purgo Biologics develops advanced biomaterials for soft tissue and bone regeneration in oral healthcare. The company manufactures bone grafts, including THE Graft™ Collagen, a porcine-derived bone mineral matrix and collagenated bone block for dental applications. It focuses on solutions for alveolar ridge preservation and GBR success.

Based in Belgrade, MT, Xtant Medical develops and provides orthobiologic solutions, including bone grafts, and complementary spinal implant systems. As a vertically integrated tissue bank, the company offers scientifically engineered biologics for a wide range of surgical procedures, empowering surgeons and improving patient outcomes.

Zimmer Biomet manufactures medical solutions, including products specifically for bone grafting and autologous therapies. The company offers a range of solutions for hard and soft tissue applications, focusing on enhancing patient mobility, joint health, and overall wellness. Their offerings support various orthopedic and reconstructive procedures.

Based in Austin, TX, ZimVie Inc. provides clinically proven solutions for dental implantology. The company manufactures biomaterials, including Puros® Allograft Bone Grafts, alongside dental implant systems and digital solutions. ZimVie's offerings aim to simplify procedures and enhance outcomes for dental practices.

Dentis USA provides a versatile range of allograft bone products for diverse surgical needs. Their offerings include a balanced 50% cortical/50% cancellous blend and 100% cortical bone. As a biomaterials provider, they aim to improve clinical outcomes with their advanced dental innovations and solutions.

Based in Jacksonville, FL, KLS Martin Manufacturing LLC develops and distributes comprehensive medical technology solutions. The company specializes in implant systems, high-frequency surgical devices, and surgical instruments, serving the surgical industry since 1896. They provide advanced medical devices, including individual patient solutions relevant to bone graft procedures.

Medtronic is a global medical technology company that manufactures a wide range of products, including spine and orthopedic solutions. They provide synthetic bone graft substitutes designed to support bone fusion and regeneration in various surgical applications for healthcare systems.

MTF Biologics processes high-quality allograft tissues for diverse clinical applications, including reconstructive surgeries, sports medicine, aesthetics, and chronic wound care. For nearly 40 years, the company has advanced tissue transplantation science, providing safe allograft options to surgeons and patients.

Based in Westborough, MA, Neoss manufactures NeoGenix Extraction Allograft, a 100% human allograft fiber. Made from demineralized bone fibers, this product is engineered for optimal bone regeneration. Neoss also provides intelligent dental solutions and implant systems for professionals, supporting predictable patient outcomes.

Regenity Biosciences, based in Paramus, NJ, is a contract development and manufacturing provider specializing in bioresorbable technologies for tissue and bone repair. They offer expertise in collagen, bioceramics, and synthetic polymers, with FDA-registered and ISO 13485-certified facilities. Their services support complex regenerative technologies for dental, spine, and orthopedic applications.

Stryker manufactures synthetic bone graft substitutes, including Vitoss, which features a unique interconnected, ultra-porous structure designed to resemble human cancellous bone. This medical technology company provides solutions for various orthopedic and spinal fusion procedures.

Subchondral Solutions manufactures the S-Core® implant system, a medical device for structural repair and stabilization of insufficient subchondral bone. The S-Core® implant addresses trabecular fractures and osteochondritis, promoting bone integration and secure fixation for soft tissue augmentation below the hyaline cartilage surface.

Based in Birmingham, AL, BioHorizons manufactures a comprehensive range of dental products, specializing in bone grafting materials, membranes, soft tissue, and wound dressing solutions. The company also produces dental implants and offers digital solutions for dental professionals throughout the United States.

BioPoly develops and manufactures innovative orthopedic implants from a unique biomaterial that combines hyaluronic acid and polyethylene. This revolutionary biomaterial provides an early-stage solution to restore joint function and improve quality of life. The company focuses on advancing materials for effective joint repair.

Based in Fremont, CA, Evolve Manufacturing specializes in complex medical and life sciences device contract manufacturing. They offer precision machining, plastic and polymer fabrication, welding, and cleanroom assembly. The company works with biocompatible materials to produce high-quality components and finished instruments for the medical industry.

Impladent Ltd. based in Northborough, MA, manufactures and distributes regenerative dental products. The company specializes in synthetic resorbable bone grafts, including OsteoGen® Plugs, Strips, and Malleable Bone Blocks. They also offer Collaform® absorbable collagen and OsteoFlex® membranes for dental procedures.

Based in Tampa, FL, LifeLink Tissue Bank operates a 54,000 square foot facility dedicated to processing human tissue. They prepare and provide allograft tissue for transplantation, including various forms of bone grafts. The organization focuses on tissue donation, processing, and distribution for surgical applications.

Based in Virginia Beach, VA, LifeNet Health processes human allograft biologic implants, providing surgeons with crucial tools for patient care. They specialize in tissue-based solutions, including bone grafts and products like Dermacell® Porous for wound management, advancing medical innovation and patient outcomes.

Based in Kettering, OH, Maxxeus manufactures musculoskeletal tissue grafts and biologic solutions for orthopedic, sports medicine, burn care, and dental fields. They provide allograft particulates, demineralized bone matrix (DBM) fillers, and structural grafts, processing tissues recovered across the United States.

Based in Lubbock, TX, Osteogenics Biomedical provides advanced tissue regeneration and implant placement solutions. The company offers products for guided bone regeneration, including high-density PTFE membranes and aorganic bovine bone-derived minerals. These materials are utilized for socket preservation and vertical augmentation of deficient alveolar ridges.

Based in Carlsbad, CA, Spinal Elements, Inc. innovates and manufactures differentiated spine technologies. They specialize in advanced biologics, providing patient-centric solutions for spine surgery. Their proprietary offerings include various bone graft solutions designed to improve patient care and address complex surgical challenges.

Stability Biologics, based in San Antonio, TX, manufactures advanced biologic products for regenerative medicine. Operating from a state-of-the-art facility, they process ethically sourced human tissue. Their portfolio includes specific bone graft materials like cortical fibers and cancellous chips, designed for a wide range of clinical applications.

Based in Warsaw, IN, WishBone Medical is a pediatric orthopedic company specializing in anatomically appropriate implants and instruments. They provide single-use, sterile packed procedure kits, including magnesium-based bone void fillers, for children suffering from orthopedic issues.

Enovis manufactures advanced bone graft solutions, including MatrixCellect® 100 DPM Putty. This demineralized bone matrix putty, derived from human bone with no added carriers, is engineered for homologous use in medical applications. The company develops products for surgeons and medical professionals.

HighRidge Medical manufactures a comprehensive portfolio of spine solutions, including synthetic bone graft materials like CopiOs Bone Void Filler Paste and allograft options such as PrimaGen Advanced™. The company also provides various interbody and spinal fixation systems, supporting innovation in spine surgery.

Integra LifeSciences develops and manufactures a diverse portfolio of medical technologies and devices for surgeons and clinicians worldwide. The company provides a range of products, including bone grafts and bone graft substitutes like the Mozaik™ line, which are used to aid and promote bone growth in surgical applications.

Isto Biologics, headquartered in Andover, MA, specializes in the development and commercialization of bone graft solutions. They offer consistent and cost-effective synthetic bone graft options, designed to aid the supply of autograft bone in the body and facilitate faster patient healing within the orthopedics sector.

Merz Biomaterials manufactures high-purity calcium hydroxyapatite (CaHA) for medical and dental applications in the United States. They supply this biocompatible ceramic for bone void filler and fixation products, implant coatings, and injectable implants. Merz customizes material specifications to meet diverse customer needs.

Redline Surgical, based in San Diego, CA, provides innovative solutions for spine surgery. They offer the VENADO Foam Strips Bone Graft System, a sterile bone graft combining purified fibrillar collagen with synthetic ceramic granules. The company focuses on operating room innovations and partners with medical technology firms for advanced spinal care.

Based in Lowell, MA, RevBio Inc. develops TETRANITE®, a revolutionary synthetic bone adhesive inspired by the sandcastle worm. This biocompatible biomaterial transforms into a cement-like adhesive scaffold, providing wet field performance for bone-to-bone and bone-to-metal applications, promising to transform bone repair.