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Reactor Manufacturers

Last updated: February 2026

This directory lists 71 reactor manufacturers across the United States, from custom pressure vessel fabricators specializing in exotic alloys to integrated system builders providing turnkey skid-mounted bioreactor trains.

Buyers in this space are typically solving for critical process needs: scaling up novel chemistry, achieving precise temperature control for exothermic reactions, managing highly viscous slurries, or preventing cross-contamination in aseptic environments. The right manufacturer brings expertise in areas like maximizing mass transfer rates, designing for extreme operating pressures, or engineering advanced Clean-in-Place (CIP) capabilities crucial for maintaining sterility.

The manufacturers represented here vary significantly in their core competencies. Some are pure-play custom fabricators, excelling in bespoke pressure vessel work using materials like Hastelloy or Inconel, and holding extensive ASME stamps. Others focus on standardized modular reactor designs, often for the pharmaceutical or biotech sectors, offering pre-validated systems with integrated control logic. Then there are specialists in agitation systems, ensuring optimal mixing and suspension for diverse fluid rheologies.

Before engaging, buyers should have their User Requirement Specification (URS), Process & Instrumentation Diagrams (P&IDs), and detailed material compatibility data well-defined. Suppliers expect clarity on operating parameters like pressure and temperature, heating/cooling requirements, and desired internal surface finish (e.g., Ra values) to accurately quote. Providing process fluid properties and anticipated cleaning regimens upfront is also critical for an accurate and safe design.

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Company Directory

71 companies nationwide

A3-USA

A3-USA designs and manufactures advanced membrane bioreactor (MBR) and sequencing batch reactor (SBR) wastewater treatment plants. Based in its North Carolina facility, the company provides reliable, high-performance solutions for municipal, industrial, and decentralized applications. Systems are engineered for efficiency, durability, and compliance.

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American Alloy Fabricators, Inc.

Based in Norristown, PA, American Alloy Fabricators, Inc. specializes in the design and manufacture of custom, ASME-certified stainless steel reactors and pressure vessels. They serve the pharmaceutical, biotechnology, chemical, and food processing industries with high-quality fabrication expertise and solutions for critical applications.

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Alloy Process Equipment, Inc.

Ventura, CA

Based in Ventura, CA, Alloy Process Equipment, Inc. manufactures custom ASME pressure vessels and process equipment. They offer engineering, design, project management, and fabrication services for vessels, custom fittings, and skid-mounted process systems. The company specializes in solutions requiring ASME, PED, and CRN certification.

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Applied Chemical Technology

Florence, AL

Based in Florence, AL, Applied Chemical Technology manufactures standard and customized process equipment, including pipe reactors, tanks, and pressure vessels for chemical process systems. They also provide comprehensive engineering, R&D, and fabrication services, supporting projects from bench-scale to commercial-scale implementation.

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BWXT

Oak Ridge, TN

BWXT manufactures naval nuclear components and reactors, a capability maintained since the 1950s, including for the USS Nautilus. The company also specializes in domestic uranium enrichment and delivers advanced TRISO nuclear fuel for microreactors, supporting national security initiatives.

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CB Mills

Gurnee, IL

Based in Gurnee, IL, CB Mills specializes in metal fabrication, providing custom reactor vessels and electro-polished reactor tanks. The company also offers custom steel fabrication, grinding mills, and mixing systems, serving industrial clients in the energy, chemical, CBD, and paint & coating sectors.

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Chemglass Life Sciences

Chemglass Life Sciences manufactures pilot plant and benchtop reactors, components, and accessories for scientific and industrial applications. They offer custom glass manufacturing, machining, and engineering services from their US-based production campus, which includes CG Machine and CG Biosciences, primarily serving the life sciences sector.

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Cotter Brothers Corporation

Based in Danvers, MA, Cotter Brothers Corporation manufactures custom bioreactor and fermentation systems for biotechnology and pharmaceutical industries. They supply single-use and stainless steel vessels. The company provides engineering and design capabilities to create efficient, high-quality process piping modules compliant with ASME and GMP standards.

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EKATO

Based in Cranberry Twp, PA, EKATO specializes in developing and scaling up advanced mixing technology solutions. The company provides crucial engineering and equipment for polymerization processes, serving industrial clients who require precise and efficient material processing within reactor systems. EKATO optimizes mixing performance for complex chemical applications.

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Fritz Industries, Inc.

Mesquite, TX

Based in Mesquite, TX, Fritz Industries, Inc. manufactures high-performance polymer reactors, offering stainless steel units from 500 to 4,500 gallons for diverse processing requirements. The company also provides custom manufacturing services and high-performance chemistry solutions for oilfield, chemistry, and biotech industries.

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General Atomics

Fort Madison, IA

General Atomics is a pioneering firm in nuclear energy, having sold its first reactor in 1958. The company is actively involved in developing breakthroughs in inertial fusion energy, accelerating paths to clean, sustainable power. General Atomics also provides defense, unmanned aircraft systems, and various commercial products.

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Hanson Tank

Los Angeles, CA

Based in Los Angeles, CA, Hanson Tank is a US manufacturer specializing in carbon and stainless steel pressure vessels. They build these industrial components to the stringent ASME Boiler and Pressure Vessel Code, serving various industries that require high-quality, code-compliant vessels essential for chemical processing and reactor applications.

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High Pressure Equipment Company

Based in Erie, PA, High Pressure Equipment Company designs and manufactures pressure vessels and reactors. They offer over 250 standard reactor designs for bench-scale and pilot plant applications. The company also provides high-pressure valves, fittings, tubing, pumps, and gas boosters.

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Holloway America

Springfield, MO

Holloway America specializes in custom engineering and fabricating stainless steel bioreactors, fermentation vessels, and batch reactors. The company provides comprehensive pressure vessel fabrication services, designing and building custom tanks and equipment for industrial clients, focusing on high-quality materials and finishes.

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Houston Vessel Manufacturing

Houston, TX

Based in Houston, TX, Houston Vessel Manufacturing (HVM) specializes in the design and fabrication of custom pressure vessels, process skids, and process piping systems. They serve industrial clients with engineered solutions for various applications, including chemical processing, oil and gas, and pharmaceutical industries.

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KULR

KULR develops custom reactors for small modular nuclear fusion systems. The company specializes in advancing clean energy technology, integrating innovative thermal management solutions into its reactor designs. KULR provides specialized manufacturing capabilities for next-generation nuclear fusion applications.

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NANO Nuclear Energy Inc.

NANO Nuclear Energy Inc. develops advanced nuclear micro modular reactors (MMR), including its KRONOS MMR and ZEUS LOKI MMR models. The company focuses on reactor technology and deployment, actively engaging with regulatory bodies and seeking commercial partners for its microreactor solutions, particularly for U.S. and international applications.

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Nviro

San Luis Obispo, CA

Nviro specializes in the design, build, and operation of water and wastewater treatment plants. They offer full-service solutions, including the provision of Sequencing Batch Reactors (SBRs) as a core product to optimize water resources. Their team self-performs services from new system construction to ongoing maintenance and technology support.

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Parr Instrument Company

Moline, IL

Parr Instrument Company, based in Moline, IL, has manufactured chemical reactors, pressure vessels, and related laboratory equipment since 1899. They provide versatile, customizable reactor systems developed for laboratory and pilot-plant scale research, focusing on quality apparatus and technical support for specialized applications.

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Paul Mueller Company

Paul Mueller Company specializes in designing and manufacturing high-quality stainless steel equipment, systems, and reactors. With over 75 years of pressure vessel experience, the company provides tailored solutions for industries including chemical, dairy, food, oil & gas, and pharmaceutical applications.

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PBS Biotech

Camarillo, CA

Based in Camarillo, CA, PBS Biotech (Progressive Biomanufacturing Systems) manufactures innovative single-use bioreactor systems. The company specializes in advanced bioreactor technology primarily for cell-based therapies and cell culture applications, serving the biopharmaceutical and life sciences industries.

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Precision Combustion, Inc.

North Haven, CT

Precision Combustion, Inc. develops and manufactures advanced catalytic and sorption devices for clean energy applications. Based in North Haven, CT, the company produces components and systems for efficient power generation, combustion, emissions control, and chemical manufacturing, including fuel processors that integrate reforming reactors for fuel cell systems.

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Phoenix Electric Corp.

Based in Canton, MA, Phoenix Electric Corp. specializes in the design and manufacture of air core reactors. With almost 50 years of experience, the company has delivered over 25,000 units into the field, providing robust solutions for various industrial applications.

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PPV CORP

Perris, CA

PPV CORP is an ASME Authorized Code company based in Perris, CA, specializing in the design, fabrication, and welding of ASME code vessels, piping, and process systems. They provide high-quality services for modular skid assembly, pressure vessels, and structural components, serving various industries with their fabrication expertise.

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RAM Industries

Waller, TX

Based in Waller, TX, RAM Industries is an ASME Code fabricator specializing in custom engineered reactors, process equipment, and pressure vessels. They focus on corrosion-resistant and heat-resistant alloys, including Titanium and Hastelloy, serving industries like chemical, petrochemical, oil & gas, and refining.

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Readco Kurimoto, LLC

Based in York, PA, Readco Kurimoto, LLC designs and manufactures high-performance continuous process systems, including industrial mixers, reactors, and blenders. Their equipment enhances product quality, consistency, and enables automated, scalable production. They also provide process development, equipment rental, maintenance, and repairs for various industrial applications.

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Reynolds Industries INC.

Fort Mill, SC

Based in Fort Mill, SC, Reynolds Industries INC. specializes in custom manufacturing jacketed reactors and heat exchangers. They provide robust industrial mixing systems for chemical applications, featuring C-coil, half pipe, internal coils, and electric heating. The company serves diverse industries like specialty chemicals, pharmaceuticals, and polymers.

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Roben Manufacturing

Lakewood, NJ

Roben Manufacturing specializes in custom dual-walled reactor vessels for pharmaceutical synthesis, API manufacturing, and sterile applications. The company also produces pressure vessels, tanks, columns, and heat exchangers, serving chemical, fine chemical, and petrochemical industries.

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R-V Industries, Inc.

Based in Honey Brook, PA, R-V Industries, Inc. provides industrial engineering and manufacturing services. They specialize in ASME pressure vessels, reactors, and columns. Serving chemical, petrochemical, food and beverage, pharmaceutical, life sciences, nuclear, and oil and gas industries, they offer design, machining, and turnkey solutions.

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Sarvatek

Augusta, GA

Based in Augusta, GA, Sarvatek manufactures innovative hardware solutions for biomanufacturing. The company provides custom bioreactors, large-scale fermentors, tanks, pipes, and valves. Sarvatek specializes in design engineering and custom fabrications, serving manufacturing and R&D centers with high-quality, cost-efficient equipment.

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Savannah Tank

Savannah, GA

Based in Savannah, GA, Savannah Tank is a custom tank manufacturer specializing in fabricating reactor vessels to exact client specifications. They utilize their expertise and facilities to produce high-quality, custom-engineered containment solutions, serving industrial clients with diverse process and application needs for various industries.

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South Gate Engineering

Chino, CA

Based in Chino, CA, South Gate Engineering specializes in custom pressure vessels and piping systems. They provide OEM solutions, offering certified ASME calculations, detailed drafting, and modeling expertise. The company adheres to strict ASME/API Codes and Standards, ensuring high quality and safety in design, development, and delivery.

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Stainless Process Systems, Inc.

Oxnard, CA

Based in Oxnard, CA, Stainless Process Systems, Inc. designs, engineers, and builds precision pressurized and non-pressurized solutions. They provide custom fabrication, welding, and repairs to ASME and NBIC code standards, holding 'U' and 'R' stamps. Services include electropolishing, serving pharmaceutical, biotech, aerospace, and nutraceutical industries.

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StaMixCo

StaMixCo designs and manufactures a diverse range of static mixers for continuous processing applications, including plug flow reactor static mixers. Specializing in high viscosity fluid processing, their products support continuous polymerization, mixing, and heat transfer for polymers, liquids, gases, slurries, and solids.

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Supercritical Fluid Technologies, Inc.

Supercritical Fluid Technologies, Inc. develops and manufactures high-pressure chemical reactors and extraction systems. Specializing in supercritical fluid extraction, reaction chemistry, and high-pressure applications, the company offers custom solutions. Their product line spans research-grade equipment to full-scale production systems for demanding material processing needs.

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THALETEC USA Inc.

Chicago, IL

THALETEC USA Inc. based in Chicago, IL, designs and manufactures innovative glass-lined equipment, including stirred reactors, storage tanks, and heat exchangers. They specialize in high-efficiency jacketed or half coil reactors for the chemical, pharmaceutical, specialty chemicals, energy, and environmental industries, also offering custom manufacturing and spare parts.

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Titanium Fabrication Corporation

Fairfield, NJ

Based in Fairfield, NJ, Titanium Fabrication Corporation (TiFab) specializes in designing and fabricating high-performance alloy reactors, pressure vessels, and related equipment. The company utilizes titanium, zirconium, Hastelloy, Inconel, and Monel. TiFab serves defense, energy, chemical, petrochemical, oil & gas, pulp & paper, and mining applications.

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Titan Metal Finishing

Camarillo, CA

Based in Camarillo, CA, Titan Metal Finishing delivers custom engineered solutions for new and existing reactors. The company specializes in metal finishing and fabricating components such as shell and tube heat exchangers, immersion coils, and tanks for diverse industrial applications including biotechnology, wastewater treatment, and semiconductor.

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TITAN Metal Fabricators

Camarillo, CA

Based in Camarillo, CA, TITAN Metal Fabricators manufactures custom engineered reactors and highly corrosion-resistant process equipment. Specializing in reactive metals like Titanium, Tantalum, and Hastelloy, they serve chemical, petrochemical, oil & gas, and nuclear power industries globally.

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TNT Industrial Contractors, Inc.

Sacramento, CA

Based in Sacramento, CA, TNT Industrial Contractors, Inc. is certified to build, repair, and alter pressure vessels and boilers per ASME Section VIII and NBIC. They provide comprehensive industrial construction, fabrication, and process piping services for diverse projects, including renewable natural gas and water treatment plants.

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USA Lab

Livonia, MI

Based in Livonia, MI, USA Lab manufactures a range of laboratory equipment including single jacketed glass reactor systems and associated heater-chillers. The company also provides various processing glassware and accessories, serving research and industrial lab applications.

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Amar Equipment

Orlando, FL

Based in Orlando, FL, Amar Equipment specializes in manufacturing continuous flow reactors and custom flow reactor designs in the USA. The company focuses on enabling efficient manufacturing processes, achieving precision in flow chemistry for industrial applications.

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Biosphere

Biosphere designs and manufactures modern, UV-enabled bioreactors for industrial biology. Replacing traditional steam bioreactors, their innovative systems utilize UV sterilization to reduce capital intensity and accelerate the scale-up of bioproducts. These simpler, cheaper, and more performant production systems support next-generation biomanufacturing.

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Applied Catalysts

Laurens, SC

Based in Laurens, SC, Applied Catalysts manufactures turn-key continuous and batch reactor systems for chemical manufacturing, alongside modular process and separation systems. They also provide catalyst development, sourcing, and testing services, offering comprehensive solutions for various chemical processes.

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Deep Fission Nuclear Energy Solutions

Deep Fission manufactures scalable 15 MWe small modular pressurized water reactors (SMRs) for underground deployment. Their "Gravity Reactors" leverage natural forces for enhanced safety and cost-efficiency, suitable for industrial sites, data centers, and remote grids.

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Enerfab

Enerfab is an experienced manufacturer specializing in the design and fabrication of half-pipe jacketed reactors. The company serves customers in the life sciences industry, leveraging skilled craftworkers, substantial shop space, and over 125 years of operational history. Enerfab emphasizes quality craftsmanship and execution.

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Niles Steel Tank

Niles Steel Tank manufactures custom stainless and carbon steel pressure vessels and tanks to ASME codes in its U.S. facility. Offering solutions for diverse industries, they feature Ultonium® glass lining for superior corrosion protection and Microban® antimicrobial technology, engineered for rigorous commercial operations.

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Oklo Inc.

Sunnyvale, CA

Based in Sunnyvale, CA, Oklo Inc. designs and deploys advanced fission power plants, including the Aurora microreactor, offering clean, reliable, and affordable energy. The company utilizes US-based R&D, engineering, and fabrication facilities for developing and commercializing next-generation nuclear reactor technology, primarily serving industrial and commercial sectors.

Email available

Syzygy Plasmonics

Houston, TX

Based in Houston, TX, Syzygy Plasmonics manufactures advanced light-powered reactors. Their modular systems, utilizing GHG e-Reforming™ technology and Rigel™ reactor cells, convert waste feedstocks into sustainable aviation fuel (SAF), methanol, syngas, and hydrogen. These innovative reactors replace traditional high-emission processes, offering lower costs and dramatically reduced emissions.

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Radiant Nuclear

Radiant Nuclear manufactures compact, portable nuclear microreactors, specifically designed to replace diesel generators. These advanced systems serve military and commercial customers, providing high energy density power solutions. The company's microreactors ensure no nuclear waste or infrastructure remains on site, offering a clean, efficient, and easily transportable energy source.

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ReelReactor, Inc.

Boise, ID

ReelReactor, Inc. based in Boise, ID, manufactures continuous micro-batch reactors designed for pure, precise, and scalable processing. Their innovative systems cater to both sensitive biological reactions and demanding chemistry applications, offering versatile and robust solutions for various industrial needs.

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Samuel Pressure Vessel Group

Lebanon, VA

Samuel Pressure Vessel Group engineers and manufactures custom pressure vessel solutions and standard air receivers for diverse industrial markets. Operating multiple manufacturing facilities across the United States, the company provides vertical and horizontal pressure vessels designed to meet specific client requirements.

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Westinghouse Nuclear

Based in Cranberry Township, PA, Westinghouse Nuclear specializes in the development of next-generation nuclear technology, including the eVinci™ Microreactor for decentralized remote applications. The company also offers a custom technology library, interactive 3D visualization tools for plant operations, and comprehensive training and resource solutions for nuclear professionals.

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Alfa Laval

Alfa Laval manufactures advanced Sequencing Batch Reactors (SBR) for activated sludge biological wastewater treatment processes. The company provides engineered solutions that support efficient and sustainable operations in various industrial applications, including data center cooling and heat reuse technologies, addressing complex processing needs across industries.

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Altam Manufacturing

Los Angeles, CA

Based in Los Angeles, CA, Altam Manufacturing designs and produces industrial equipment, including pressure vessels, steam sterilizers, and autoclaves. The company provides steel welding and fabrication services for bespoke solutions, adhering to AWS/ASME codes, serving diverse industries.

Phone available

Bendel

Indianapolis, IN

Bendel specializes in the custom design and fabrication of ASME reactors for chemical, petrochemical, food & beverage, and textile manufacturing. They also provide custom process vessels, heat exchangers, distillation columns, and API storage tanks, supporting customers across all phases of the oil and gas value chain with engineering and fabrication expertise.

Phone available

Buckeye Fabricating

Springboro, OH

Buckeye Fabricating specializes in designing and manufacturing custom ASME code certified steel reactor vessels and pressure vessels. With over 50 years of experience, the company provides comprehensive fabrication services for complex tank products, managing projects from inquiry to delivery for various industrial applications.

Phone available

Elutriate Systems

Elutriate Systems manufactures Bio Reactors specializing in the efficient reduction of high Biological Oxygen Demand (BOD) in effluent. Their reactors provide effective wastewater treatment solutions for industrial and commercial clients, facilitating environmentally responsible discharge for land application or sewer systems.

Phone available

Kairos Power

Alameda, CA

Based in Alameda, CA, Kairos Power develops, builds, and deploys advanced fluoride salt-cooled high-temperature reactors. The company focuses on transforming the clean energy ecosystem by reimagining how advanced reactors are developed, built, and deployed at scale, delivering safe and affordable nuclear energy.

Phone available

Kennedy Tank and Manufacturing Co., Inc.

Indianapolis, IN

Based in Indianapolis, IN, Kennedy Tank and Manufacturing Co. Inc. specializes in custom fabrication and field servicing of large storage tanks, pressure vessels, heat exchangers, and reactors. They manufacture, inspect, test, and stamp vessels to ASME code, offering comprehensive solutions for industrial and commercial partners.

Phone available

McKenna Engineering

Carson, CA

McKenna Engineering provides custom systems fabrication and skid-mounted process systems for industries handling air, gas, liquids, and dry bulk solids. Based in Carson, California, their 18,000SF facility offers engineering, modular fabrication, construction, installation, and equipment services for various industrial applications.

Phone available

Mettler Toledo

Columbus, OH

Mettler Toledo provides chemical synthesis reactors designed for precise and automated control of critical process parameters. These versatile, data-rich solutions enhance scientific research and development workflows. The company focuses on delivering high-quality instrumentation for various laboratory and industrial applications.

Phone available

Caid Industries

Big Lake, MN

Based in Big Lake, MN, Caid Industries designs and manufactures pressure vessels for diverse industrial applications. Leveraging over seven decades of experience since 1947, the company provides robust fabrication solutions. Their expertise directly supports reactor manufacturing needs, offering specialized containment vessels for critical industrial processes.

Phone available

SFI

Springfield, MO

Based in Springfield, MO, SFI designs and builds custom stainless steel pressure vessels and reactors. They fabricate equipment to meet customer application requirements and ASME Code standards. Services include both on-site and in-shop manufacturing of tanks for industrial clients.

Phone available

TransTech Energy

Spring, TX

Based in Spring, TX, TransTech Energy specializes in the custom design and fabrication of large diameter, heavy wall, ASME code certified pressure vessels. They provide robust engineering and manufacturing solutions for super capacity pressure containment, serving industrial clients with complex and critical vessel requirements.

Phone available

TransTech Fabrication

TransTech Fabrication specializes in the custom design and fabrication of Chemical & Process Manufacturing Reactors, built to exact client specifications. The company provides extensive fabrication, installation, maintenance, and repair services for process pipe modules, ASME storage tanks, and industrial gas and cryogenic solutions, serving various energy sectors.

Phone available

Woven Metal Products, Inc.

Alvin, TX

Based in Alvin, TX, Woven Metal Products, Inc. specializes in custom metal fabrication, particularly high-precision reactor and tower internals. They provide light, medium, and heavy fabrication services, working with diverse metals and specialty alloys. WMP serves the chemical, petrochemical, oil & gas, and renewable energy sectors.

Phone available

X-energy

Based in Rockville, MD, X-energy is an advanced nuclear reactor and fuel company. It develops Generation IV high-temperature gas-cooled small modular reactors (SMRs), notably the Xe-100 model. The company also manufactures TRISO-X fuel, engineered for extreme temperatures and passive safety, delivering zero-emissions energy solutions.

Phone available

Holtec International

Camden, NJ

Holtec International designs and manufactures the SMR-300 small modular reactor at its Krishna P. Singh Technology Campus in Camden, New Jersey. This technology company also specializes in nuclear plant decommissioning, nuclear fuel and waste management. They provide heat transfer equipment and engineering services for the nuclear industry.

No contact on file

NuScale Power

Portland, OR

NuScale Power develops and commercializes innovative small modular reactor (SMR) technology. The company designs, builds, and deploys scalable nuclear power plants for electricity generation and various industrial applications. They offer advanced reactor solutions for clean energy needs globally.

No contact on file

Mersen

Bay City, MI

Based in Bay City, MI, Mersen is a global expert in electrical power and advanced materials. The company develops and manufactures high-technology chemical reactors for continuous flow systems, often in cooperation with partners. Mersen Boostec's specialized manufacturing capabilities serve various industries.

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How to Choose a Company

  • Verify the manufacturer holds the necessary ASME Boiler and Pressure Vessel Code (BPVC) certifications (e.g., U-stamp, R-stamp) for your specific pressure and temperature requirements. For vessels intended for European markets, ensure they can provide PED (Pressure Equipment Directive) compliance documentation.
  • Assess their experience with the specific construction materials required for your process, especially if dealing with corrosive or high-purity media (e.g., Hastelloy, Duplex Stainless Steel, Titanium, or specialized coatings). Request to see their Welding Procedure Specifications (WPS) and Welder Performance Qualifications (WPQ) relevant to your chosen alloy.
  • Evaluate their proven capability in designing and integrating agitation systems specific to your fluid rheology and process goals. This includes impeller type selection (e.g., Rushton, hydrofoil, pitched-blade), baffle design, and motor sizing for achieving desired blend times, solid suspension, or gas dispersion without excessive shear.
  • Confirm their expertise in engineering appropriate heat transfer surfaces – whether jacketed, half-pipe coil, or internal coils – to maintain precise temperature control during exothermic or endothermic reactions. Request calculations for heat transfer coefficients and verification of available utilities (steam, chilled water) matching their design.
  • Beware of manufacturers who are vague about long-term spare parts availability, post-installation support, or don't provide comprehensive documentation packages including material traceability records, NDT reports (e.g., radiography, ultrasonic testing), and as-built drawings. Inadequate lifecycle support can severely impact operational uptime and future regulatory audits.

Frequently Asked Questions

How critical is the internal surface finish (Ra value) for a reactor, and what factors influence it?

The internal surface finish, typically measured in Ra (roughness average) micrometers, is extremely critical, especially for pharmaceutical, biotech, and high-purity chemical applications. A smoother finish (lower Ra value, e.g., <15 Ra for biopharma) minimizes product adhesion, biofilm formation, and allows for more effective Clean-in-Place (CIP) or Sterilize-in-Place (SIP) operations. Factors influencing it include the base material quality, welding techniques, grinding, and electropolishing. Always specify the required Ra value in your URS.

When should I consider a skid-mounted reactor system versus individual components?

Skid-mounted reactor systems, often referred to as 'reactor trains,' offer significant advantages for complex processes, limited facility space, or situations requiring rapid deployment. They arrive pre-piped, pre-wired, and pre-tested, reducing on-site installation time, commissioning, and potential integration errors. They are ideal for modular expansion or processes needing dedicated utility connections. Individual components might be more cost-effective for simpler, standalone reactors or where extensive customization of piping runs is preferred within an existing facility.

What Non-Destructive Testing (NDT) methods should I expect for my custom reactor fabrication?

For custom reactor fabrication, a robust NDT plan is crucial for quality and safety. Common methods include Visual Testing (VT) for all welds, Dye Penetrant Testing (PT) for surface cracks, and Radiographic Testing (RT) or Ultrasonic Testing (UT) for detecting internal flaws in critical welds, especially on pressure boundaries. Magnetic Particle Testing (MT) is also used for ferromagnetic materials. The specific NDT requirements will depend on your operating pressure, temperature, material type, and applicable ASME code specifications.

How do I ensure material traceability and quality for critical reactor components?

Ensuring material traceability starts with demanding Mill Test Reports (MTRs) for all primary components like vessel shells, heads, nozzles, and internal parts. These MTRs verify the chemical composition and mechanical properties of the raw material. The manufacturer should have a robust material control system that links these MTRs to each fabricated part, often through heat numbers or unique identifiers. This is paramount for regulatory compliance, especially in GMP environments, and for future troubleshooting or repairs, ensuring you can always confirm the origin and specification of every material used.

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